Protein : DLL4

Hugo ID 2910
Name DLL4
Description delta-like 4 (Drosophila) (predicted)
Notes This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.
Owner Public
URN urn:agi-llid:54567
Connectivity 91

Source Curated

GenBank ID NC_000015
NM_019074
NP_061947
NT_010194
NW_925840
AC_000058
AC020661
AB036931
BAB16085
AB043894
BAB18581
AF253468
AAF76427
AF279305
AAF81912
AY358894
AAQ89253
BC106950
AAI06951
BI820351
Q9NR61
NC_000068
NM_019454
NP_062327
NT_039207
NW_000178
NW_001030694
AC_000024
AL929318
AB043893
BAB18580
AF253469
AAF76428
AF273454
AAF78785
AK004739
BAB23520
AK031699
AK052322
AK165517
AK171717
BC042497
AAH42497
BC049130
AAH49130
Q9JI71
NC_005102
XM_230472
XP_230472
NW_001084813
XM_001080829
XP_001080829
NW_047657
AC_000071

LocusLink ID 54567
54485
311332

Organism Homo sapiens
Mus musculus
Rattus norvegicus

OMIM ID 605185

Alias hdelta2
MGC126344
delta-like 4 protein
delta 4 precursor
delta ligand 4 precursor
notch ligand DLL4 precursor
notch ligand delta-2 precursor
delta-like 4 homolog (Drosophila)
Delta4
delta-like 4
delta-like 4 (Drosophila) (predicted)

GO ID 0005112
0005509
0007219
0030154
0008015
0007165
0016021
0016020
0020037
0005515
0001525
0007154
0007275
0005887

Swiss-Prot Accession Q9NR61
Q9JI71

Unigene ID Hs.511076
Mm.143719

RGD ID 1309740

MGI ID 1859388

Cell Localization Extracellular

Pathway NOTCH1 -> EP300 signaling pathway
NOTCH1 -> LEF1 signaling pathway
NOTCH1 -> MEF2C signaling pathway
NOTCH1 -> MYOD1 signaling pathway
NOTCH1 -> NF-kB signaling pathway
NOTCH1 -> SMAD3 signaling pathway

Group Ligands
development
cell communication
cell differentiation
signal transduction
Notch signaling pathway
angiogenesis
circulation
membrane
integral to membrane
integral to plasma membrane
protein binding
calcium ion binding
Notch binding
heme binding