Protein : NOTCH1

Hugo ID

7881

Name

NOTCH1

Description

Notch gene homolog 1 (Drosophila)

Notes

transmembrane receptor; involved in cell-cell interactions important for development and pattern formation [RGD]

Owner

Public

URN

urn:agi-llid:4851

Connectivity

570


Source

Curated


GenBank ID

NC_000009

NM_017617

NP_060087

NT_024000

NW_924573

AC_000052

AL354671

CAI16149

AL592301

CAI13934

AB209873

BAD93110

AF308602

AAG33848

AK000012

BAA90883

BC013208

CR457221

CAG33502

M73980

AAA60614

P46531

Q59ED8

Q5SXM3

Q6IAD4

Q9NXX4

NC_000068

NM_008714

NP_032740

NT_039206

NW_000174

NW_001030686

AC_000024

AB100603

BAC77038

BAC77039

BAC77040

AL732541

AB101624

AB101625

AB101626

AB101627

AB101628

AB101629

AB101630

AB101631

AB101634

AB101636

AB101637

AF508809

AAM28905

AJ238029

CAB40733

AK004408

AK042197

BAC31194

AK054089

AK075572

AK079454

AK090118

AK149054

AK154528

BAE32653

AK157475

BAE34095

BC010325

BC023886

BE952133

L02613

AAK14898

X68278

CAA48339

X82562

CAA57909

Z11886

CAA77941

Z21925

Q01705

NC_005102

XM_342392

XP_342393

NW_001084810

XM_001078434

XP_001078434

NW_047651

AC_000071

X57405

CAA40667

Q07008


LocusLink ID

4851

18128

25496


Organism

Homo sapiens

Mus musculus

Rattus norvegicus


OMIM ID

190198


Alias

hN1

TAN1

notch1

neurogenic locus notch homolog protein 1

translocation-associated notch protein TAN-1

Mis6

lin-12

9930111A19Rik

Notch gene homolog 1

major type A protein

transmembrane receptor Notch1

transmembrane receptor Notch1 B

transmembrane receptor Notch1 D

NOTCH

Notch gene homolog 1 (Drosophila)

Drosophila Notch homolog 1

Drosophila Notch homolog 1 (controlling the the ectodermal and neural cell fate in Drosophila)


GO ID

0005509

0005515

0004872

0007219

0030154

0006955

0045662

0050793

0006355

0006350

0016021

0016020

0005634

0003677

0003682

0003700

0042640

0007409

0048754

0045165

0001708

0007386

0007368

0007275

0035116

0030326

0007492

0008544

0001837

0030900

0007440

0010001

0031069

0007507

0030216

0030324

0043066

0045596

0045665

0048663

0043065

0008284

0045944

0050678

0006357

0048103

0002040

0005737

0005615

0009790


Swiss-Prot Accession

P46531

Q59ED8

Q5SXM3

Q6IAD4

Q9NXX4

Q01705

Q07008


Unigene ID

Hs.495473

Mm.290610

Mm.392411


RGD ID

3187


MGI ID

97363


Cell Localization

Plasma membrane


Microarray ID

218902_at


Pathway

NOTCH1 -> EP300 signaling pathway

NOTCH1 -> LEF1 signaling pathway

NOTCH1 -> MEF2C signaling pathway

NOTCH1 -> MYOD1 signaling pathway

NOTCH1 -> NF-kB signaling pathway

NOTCH1 -> SMAD3 signaling pathway












Group

Receptors

development

cell differentiation

Notch signaling pathway

glial cell differentiation

cell fate commitment

keratinocyte differentiation

axonogenesis

epithelial to mesenchymal transition

neuron fate commitment

negative regulation of neuron differentiation

cell fate specification

negative regulation of myoblast differentiation

negative regulation of cell differentiation

negative regulation of apoptosis

positive regulation of apoptosis

somatic stem cell division

regulation of epithelial cell proliferation

positive regulation of cell proliferation

transcription

positive regulation of transcription from RNA polymerase II promoter

regulation of transcription, DNA-dependent

regulation of transcription from RNA polymerase II promoter

embryonic development

regulation of development

forebrain development

embryonic limb morphogenesis

embryonic hindlimb morphogenesis

hair follicle morphogenesis

branching morphogenesis of a tube

heart development

sprouting angiogenesis

foregut morphogenesis

lung development

endoderm development

epidermis development

anagen

compartment specification

determination of left-right symmetry

immune response

membrane

cytoplasm

nucleus

integral to membrane

extracellular space

chromatin binding

protein binding

calcium ion binding

DNA binding

transcription factor activity

receptor activity