Protein : JAG1

Hugo ID

6188

Name

JAG1

Description

jagged 1

Notes

ligand responsible for activating Notch1 [RGD]

Owner

Public

URN

urn:agi-llid:182

Connectivity

260


Source

Curated


GenBank ID

NC_000020

NM_000214

NP_000205

NT_011387

NW_927317

AC_000063

AL035456

CAC07198

AF003837

AAC51731

AF028593

AAB84053

BC098393

AAH98393

U61276

AAB39007

U73936

AAC52020

U77720

AAC51323

U77914

AAC50909

P78504

Q99740

NC_000068

NM_013822

NP_038850

NT_039207

NW_000178

XM_990538

XP_995632

NW_001030694

AC_000024

AL713981

AA880220

AF171092

AAF15505

AK078018

BAC37099

AK137092

BAE23235

AK162228

BAE36803

BC058675

AAH58675

Q9QXX0

NC_005102

NM_019147

NP_062020

NW_001084813

NW_047658

AC_000071

L38483

AAB06509

Q63722


LocusLink ID

182

16449

29146


Organism

Homo sapiens

Mus musculus

Rattus norvegicus


OMIM ID

601920

118450

187500


Alias

AGS

AHD

AWS

HJ1

CD339

JAGL1

MGC104644

jagged 1

jagged1 (Alagille syndrome)

Htu

Ser-1

slalom

Serrate-1

Headturner

Jagged 1 (Alagille syndrome)


GO ID

0005112

0005509

0008083

0005198

0007219

0001525

0007154

0001709

0007275

0045446

0030097

0030216

0045445

0007399

0030334

0042127

0005576

0005887

0016020

0005515

0042491

0048839

0002011

0045596

0009887

0045747

0045639

0005615

0016021

0005886


Swiss-Prot Accession

P78504

Q99740

Q9QXX0

Q63722


Unigene ID

Hs.590881

Mm.22398

Rn.88804


RGD ID

2937


MGI ID

1095416


Cell Localization

Extracellular


Microarray ID

216268_s_at

209098_s_at

209099_x_at

231183_s_at

33178_at

35414_s_at

236678_at


Pathway

Notch -> CREB1 signaling pathway

Notch -> ELK1-SRF signaling pathway

Notch -> ELK4-SRF signaling pathway

Notch -> MYC signaling pathway

Notch -> TCF3 signaling pathway

NOTCH1 -> EP300 signaling pathway

NOTCH1 -> LEF1 signaling pathway

NOTCH1 -> MEF2C signaling pathway

NOTCH1 -> MYOD1 signaling pathway

NOTCH1 -> NF-kB signaling pathway

NOTCH1 -> SMAD3 signaling pathway

Notch -> CBF1 signaling pathway








Group

Ligands

development

cell communication

Notch signaling pathway

positive regulation of Notch signaling pathway

endothelial cell differentiation

keratinocyte differentiation

cell fate determination

auditory receptor cell differentiation

myoblast differentiation

positive regulation of myeloid cell differentiation

negative regulation of cell differentiation

regulation of cell migration

regulation of cell proliferation

organ morphogenesis

morphogenesis of an epithelial sheet

angiogenesis

hemopoiesis

inner ear development

nervous system development

extracellular region

membrane

plasma membrane

integral to membrane

integral to plasma membrane

extracellular space

structural molecule activity

protein binding

calcium ion binding

growth factor activity

Notch binding