DirectRegulation :

Owner Public
URN urn:agi-DirectRegulation:inout-urn:agi-llid:28514:out-urn:agi-llid:4851::positive:direct interaction
Entities DLL1 --+> NOTCH1
References 2
Connectivity 2
Effect positive
Mechanism direct interaction

Sentence The overlapping expression patterns of the Dll1 and Notch1 genes suggest that cells in these tissues can communicate by interaction of the Dll1 and Notch1 proteins.
Source Curated
Organism C-elegans
Organ nervous system
Tissue mesoderm
MedLine Reference 7671806:10

Sentence Jagged1 activates both Notch1 and Notch2, whereas Delta-like 1 (Dll1) can activate only Notch1 efficiently ( 46 ).
Journal Mol. Cell. Biol
Source Curated
Journal Reference v21 i17 p6071 (2001)
Journal Link http://mcb.asm.org/cgi/content/full/21/17/6071
Organism mouse
MedLine Reference 11486044:1130