Binding :

Connectivity 2
Owner Public
URN urn:agi-Binding:inout-urn:agi-llid:4851:inout-urn:agi-llid:2033:
Entities EP300 ---- NOTCH1
References 10

MedLine Reference 11604511:8
Sentence In addition, the interaction of mammalian Notch-1-IC with p300 was destabilized after deletion of the EP domain of Notch-1-IC.
Organism Mus musculus

MedLine Reference 12391150:1128
Sentence After pelleting and washing the M 2-agarose beads, the proteins were eluted and levels of p300 associated with Notch1 IC, Notch3 IC, and MAML1 were determined by Western blotting with an antibody against p300.
Journal Mol. Cell. Biol
Journal Reference v22 i22 p7812 (2002)
Journal Link http://mcb.asm.org/cgi/content/full/22/22/7812
Organism Mus musculus
CellLineName Sf9

Organism Mus musculus

Organism Mus musculus

Organism Mus musculus

Organism Mus musculus

Organism Mus musculus

Organism Mus musculus

MedLine Reference 12391150
Sentence p300 interacts with Notch1. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and mouse Notch1
Source Curated

MedLine Reference 11604511:1400
Sentence From our pull-down experiments, one could speculate that in addition to the EP domain, C-terminal sequences might be necessary for full p300 binding to Notch-1 in vivo.
Journal Mol. Cell. Biol
Journal Reference v21 i22 p7761 (2001)
Journal Link http://mcb.asm.org/cgi/content/full/21/22/7761
Organism Mus musculus
Source Curated